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Why Testosterone Matters

Testosterone is a hormone that can stimulate prostate cancer growth

Growth and function of the prostate gland depend on testosterone, a male sex hormone (or androgen) made mainly in the testicles.

Cancer of the prostate gland develops when cells of the prostate show uncontrolled growth—high levels of testosterone help fuel this growth.

The goal of androgen deprivation therapy (ADT) is to lower the level of testosterone in the body

In the treatment of advanced prostate cancer (APC)

FIRMAGON® takes a different path to testosterone suppression than Lupron Depot® (leuprolide acetate)

Chart of different testosterone suppression of Firmagon and Lupron Depot
Get to T goal fast with FIRMAGON

Lupron Depot is a registered trademark of ABBVIE ENDOCRINE INC.


FIRMAGON® (degarelix for injection) is a gonadotropin-releasing hormone (GnRH) antagonist that immediately stops testosterone production at its source, eliminating the possibility of an initial testosterone “surge” and any need for additional therapies to counteract surges.

FIRMAGON is the only
gonadotropin-releasing hormone (GnRH) antagonist available in the United States for the treatment of advanced prostate cancer (APC).


Lupron Depot triggers a receptor called the luteinizing hormone–releasing hormone (LHRH) receptor, which results in an initial surge in testosterone. This initial surge subsequently reduces over a few weeks. Additional medication may be required to prevent the effects of the testosterone surge.

Get to T goal fast with FIRMAGON

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