AFTER EACH FIRMAGON^® INJECTION

The essentials of post-injection care

The injection site itself affects people differently. Some patients experienced reactions at the injection site after the first dose (35%), but these reactions typically reduced to 4% with
the smaller maintenance injections that followed every 28 days.

Reactions at the injection site may include temporary redness, slight pain, and swelling and/or a lump under the skin.* Most injection site reactions are usually mild to moderate and decrease within 3 days.

Remember to care for the injection site using the guidelines below

*This lump is a storage of FIRMAGON (also called a “depot”) that supplies your body with a continuous release of FIRMAGON over time.

This lump is a storage of FIRMAGON (also called a “depot”) that supplies your body with a continuous release of FIRMAGON over time.

Simple ways to take
care of the injection site

Keep the injection site clean

Wear comfortable, loose-fitting clothing that does not rub against the injection site

Avoid rubbing or scratching the area

Plan to choose a different location than the site of the last injection, and avoid receiving an injection at or near areas where adverse skin reactions occurred in the past

Possible side effects of FIRMAGON in the treatment of patients with advanced prostate cancer (APC)

FIRMAGON can cause serious side effects, including:

Serious allergic reactions. Get medical help right away if you get any of these symptoms:
- Trouble breathing or wheezing
- Severe itching
- Swelling of your face, lips, mouth, or tongue
Disorder of the heart’s electrical activity. Your healthcare provider may do tests during treatment with FIRMAGON to check your heart for a condition called long QT syndrome.

The common side effects of FIRMAGON include:

Injection site pain, redness, and swelling
Hot flashes
Weight gain
Increase in some liver enzymes

Other side effects include decreased sex drive and erectile function problems.

Tell your healthcare provider if you have any side effect that bothers you or that does not go away. These are not all the possible side effects.

Call your doctor for medical advice about side effects. You may report side effects to the FDA
at 1-800-FDA-1088.

Never hesitate to talk with your treatment team about any concerns you have after an injection

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Indication

FIRMAGON^® (degarelix for injection) is a prescription medicine used in the treatment of advanced prostate cancer.

Important Safety Information

Do not take FIRMAGON if you are allergic to any of the ingredients in FIRMAGON. FIRMAGON can cause serious allergic reactions. Get medical help right away if you get any of these symptoms:
- Trouble breathing or wheezing
- Severe itching
- Swelling of your face, lips, mouth, or tongue

Women who are pregnant or may become pregnant should not take FIRMAGON. FIRMAGON can harm an unborn baby when given to a pregnant woman.
Before receiving FIRMAGON, tell your healthcare provider about all your medical conditions, including if you have any heart problems including a condition called long QT syndrome, have problems with blood levels such as sodium, potassium, calcium, and magnesium, have kidney or liver problems.
The common side effects of FIRMAGON include: hot flashes, injection site pain, redness and swelling, weight gain, increase in some liver enzymes, decreased sex drive, and erectile function problems.

Tell your healthcare provider if you have any side effects that bother you or that does not go away. These are not all the possible side effects. You may report side effects to FDA at 1-800-FDA-1088.